Product Name :
S-23
Description:
S-23 is an orally active selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. S-23 induces androgen receptor (AR)-mediated transcriptional activation in CV-1 cells. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats.
CAS:
1010396-29-8
Molecular Weight:
416.75
Formula:
C18H13ClF4N2O3
Chemical Name:
(2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide
Smiles :
C[C@](O)(COC1C=C(F)C(Cl)=CC=1)C(=O)NC1C=C(C(=CC=1)C#N)C(F)(F)F
InChiKey:
SSFVOEAXHZGTRJ-KRWDZBQOSA-N
InChi :
InChI=1S/C18H13ClF4N2O3/c1-17(27,9-28-12-4-5-14(19)15(20)7-12)16(26)25-11-3-2-10(8-24)13(6-11)18(21,22)23/h2-7,27H,9H2,1H3,(H,25,26)/t17-/m0/s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.{{Umifenovir} web|{Umifenovir} SARS-CoV|{Umifenovir} Technical Information|{Umifenovir} Data Sheet|{Umifenovir} custom synthesis|{Umifenovir} Cancer}
Shelf Life:
≥12 months if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
S-23 is an orally active selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. S-23 induces androgen receptor (AR)-mediated transcriptional activation in CV-1 cells. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats.|Product information|CAS Number: 1010396-29-8|Molecular Weight: 416.75|Formula: C18H13ClF4N2O3|Chemical Name: (2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano-3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide|Smiles: C[C@](O)(COC1C=C(F)C(Cl)=CC=1)C(=O)NC1C=C(C(=CC=1)C#N)C(F)(F)F|InChiKey: SSFVOEAXHZGTRJ-KRWDZBQOSA-N|InChi: InChI=1S/C18H13ClF4N2O3/c1-17(27,9-28-12-4-5-14(19)15(20)7-12)16(26)25-11-3-2-10(8-24)13(6-11)18(21,22)23/h2-7,27H,9H2,1H3,(H,25,26)/t17-/m0/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Solubility: DMSO : 100 mg/mL (239.{{Pyrotinib} site|{Pyrotinib} Protein Tyrosine Kinase/RTK|{Pyrotinib} Technical Information|{Pyrotinib} In stock|{Pyrotinib} supplier|{Pyrotinib} Epigenetics} 95 mM; Need ultrasonic).PMID:23319057 |Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥12 months if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|How to use|In Vitro:|S-23 induces AR-mediated transcriptional activation in CV-1 cells when used at a concentration of 10 nM.|In Vivo:|By administration of S-23 to castrated animals, androgen-dependent organ weights increased in a dose-dependent manner. The ED50 of S-23 in the prostate and levator ani muscle is 0.43 and 0.079 mg/d, respectively.|Products are for research use only. Not for human use.|
