Combined with optimistic and adverse collection of phosphorylation motifs may be theCombined with constructive and

Combined with optimistic and adverse collection of phosphorylation motifs may be the
Combined with constructive and unfavorable choice of phosphorylation motifs will be the basis for context-dependent mitotic signaling. Sci. Signal. four: ra42. Anisimov, A., V. M. Leppanen, D. Tvorogov, G. Zarkada, M. Jeltsch et al., 2013 The basis for the distinct biological activities of vascular endothelial development issue receptor-1 ligands. Sci. Signal. 6: ra52. Besse, A., B. Lamothe, A. D. Campos, W. K. Webster, U. Maddineni et al., 2007 TAK1-dependent signaling demands functional interaction with TAB2/TAB3. J. Biol. Chem. 282: 3918928. Bisson, N., M. Tremblay, F. Robinson, D. R. Kaplan, S. P. Trusko et al., 2008 Mice lacking both mixed-lineage kinase genes Mlk1 and Mlk2 retain a wild variety phenotype. Cell Cycle 7: 90916. Bock, B. C., P. O. Vacratsis, E. Qamirani, and K. A. Gallo, 2000 Cdc42-induced activation on the mixed-lineage kinase SPRK in vivo. Requirement of the Cdc42/Rac interactive binding motif and modifications in phosphorylation. J. Biol. Chem. 275: 142314241. Boutros, M., H. Agaisse, and N. Perrimon, 2002 Sequential activation of signaling pathways through innate immune responses in Drosophila. Dev. Cell 3: 71122. Brancho, D., J. J. Ventura, A. Jaeschke, B. Doran, R. A. Flavell et al., 2005 Function of MLK3 within the regulation of mitogen-activated protein kinase signaling cascades. Mol. Cell. Biol. 25: 3670681. Brand, A. H., and N. Perrimon, 1993 Targeted gene expression as a indicates of altering cell fates and creating dominant phenotypes. Development 118: 40115. Calleja, M., E. Moreno, S. Pelaz, and G. Morata, 1996 Visualization of gene expression in JAK1 Inhibitor Formulation living adult Drosophila. Science 274: 25255. Chang, L., and M. Karin, 2001 Mammalian MAP kinase signalling cascades. HDAC11 Inhibitor supplier Nature 410: 370. Chen, J., E. M. Miller, and K. A. Gallo, 2010 MLK3 is critical for breast cancer cell migration and promotes a malignant phenotype in mammary epithelial cells. Oncogene 29: 4399411. Chen, W., M. A. White, and M. H. Cobb, 2002 Stimulus-specific requirements for MAP3 kinases in activating the JNK pathway. J. Biol. Chem. 277: 491059110. Collins, C. A., Y. P. Wairkar, S. L. Johnson, and a. Diantonio, 2006 Highwire restrains synaptic development by attenuating a MAP kinase signal. Neuron 51: 579. Conner, S. H., G. Kular, M. Peggie, S. Shepherd, A. W. Schuttelkopf et al., 2006 TAK1-binding protein 1 is often a pseudophosphatase. Biochem. J. 399: 42734. Craig, E. A., M. V. Stevens, R. R. Vaillancourt, and T. D. Camenisch, 2008 MAP3Ks as central regulators of cell fate through development. Dev. Dyn. 237: 3102114. Cronan, M. R., K. Nakamura, N. L. Johnson, D. A. Granger, B. D. Cuevas et al., 2012 Defining MAP3 kinases essential for MDA-MB-231 cell tumor development and metastasis. Oncogene 31: 38893900. Cuevas, B. D., A. N. Abell, and G. L. Johnson, 2007 Part of mitogen-activated protein kinase kinase kinases in signal integration. Oncogene 26: 3159171. Delaney, J. R., S. Stoven, H. Uvell, K. V. Anderson, Y. Engstrom et al., 2006 Cooperative control of Drosophila immune responses by the JNK and NF-kappaB signaling pathways. EMBO J. 25: 3068077. Drysdale, R., and C. Flybase, 2008 FlyBase: a database for the Drosophila research neighborhood. Strategies Mol. Biol. 420: 459. Du, Y., B. C. Bock, K. A. Schachter, M. Chao, and K. A. Gallo, 2005 Cdc42 induces activation loop phosphorylation and membrane targeting of mixed lineage kinase three. J. Biol. Chem. 280: 429842993. Freeman, M., 1996 Reiterative use on the EGF receptor triggers differentiation of all cell kinds inside the Drosophila eye. Cell 87: 65160. G.