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Mathematical strategies, but you can find situations where unique data kinds are requiredare needed mathematical strategies, but you’ll find cases where particular information kinds or assumptions are created to define functions in between mean, variance, and input elements. elemen assumptions are made to define functions amongst mean, variance, and input NNs, which have not too long ago been extensively applied in artificial intelligence, can present straightforward NNs, which have recently been extensively applied in artificial intelligence, can present sim mathematical models (functions) making use of artificial Glycodeoxycholic Acid MedChemExpress neurons artificial neurons and figure out unkno mathematical models (functions) employing and ascertain unknown interactions among the input and output overall performance of a process without the need of any information of interactions involving the input and output performance of a procedure without a the principle. understanding of the principle. This study hasThis study has described a functional-link-NN-based estimation technique that off described a functional-link-NN-based estimation system that offers an alternative RD alternative with no assumptions inherent within the conventional LSM-based LSM-ba an method RD strategy without assumptions inherent inside the conventional RSM. Compared with the current RD dual-response estimation strategy, the proposed propo RSM. Compared together with the existing RD dual-response estimation approach, the technique supplies significant benefits in figuring out the functional technique provides important benefits in figuring out the functional connection betweenrelations amongst output performances output performances along with the proposed the manage elements as well as the control elements andand the optimal solutions. the optimal options. T dual-response proposed dual-response estimation strategy is often speedily and efficiently implemen estimation method may be immediately and effectively implemented employing MATLAB (see applying MATLABExperimental final Orotidine MedChemExpress results show that the proposedthat the proposed N Appendix B). (see Appendix B). Experimental final results show NN-based primarily based estimation better solutions thanbetter options than the standard LSM-ba estimation technique can realize technique can achieve the traditional LSM-based RSM in RSM within the EQL metric. the EQL metric. In proposed the proposed functional-link-NN-based dual-response RD Inside the future, the the future, functional-link-NN-based dual-response RD estimation estimat method will likely be extended and multiple-response optimization complications. method might be extended to time series datato time series information and multiple-response optimizat Also, weproblems. Also, we plan to look for the optimal the neuralby binary coding plan to search for the optimal structure by binary coding structure network neural network structure using a genetic algorithm and conducting research on optimiz the weights on the neural network.Author Contributions: Conceptualization, T-H.L. and S.S.; Methodology, T-H.L. and S Modeling, T-H.L.; Validation T-H.L. and S.S.; Writing–Original Draft Preparation, T-H.L. and SAppl. Sci. 2021, 11,11 ofAppl. Sci. 2021, 11, x FOR PEER REVIEWstructure using a genetic algorithm and conducting research on optimizing the weights of 12 of 20 the neural network.Author Contributions: Conceptualization, T.-H.L. and S.S.; Methodology, T.-H.L. and S.S.; Modeling, T.-H.L.; Validation T.-H.L. and S.S.; Writing–Original Funding Acquisition, S.S. and S.S.; Writing– Writing–Review and Editing, M.T., J.H.J., H.J., and S.S.; Draft Preparation,.

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Author: Potassium channel