CTDSP2 Antibody (4F4) Summary
| Immunogen |
CTDSP2 (AAH65920, 1 a.a. ~ 272 a.a) full length recombinant protein with GST tag.MEHGSIITQARREDALVLTKQGLVSKSSPKKPRGRNIFKALFCCFRAQHVGQSSSSTELAAYKEEANTIAKSDLLQCLQYQFYQIPGTCLLPEVTEEDQGRICVVIDLDETLVHSSFKPINNADFIVPIEIEGTTHQVYVLKRPYVDEFLRRMGELFECVLFTASLAKYADPVTDLLDRCGVFRARLFRESCVFHQGCYVKDLSRLGRDLRKTLILDNSPASYIFHPENAVPVQSWFDDMADTEL
|
| Localization |
Nuclear
|
| Specificity |
CTDSP2 – CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
|
| Isotype |
IgG2a Kappa
|
| Clonality |
Monoclonal
|
| Host |
Mouse
|
| Gene |
CTDSP2
|
| Purity |
IgG purified
|
| Innovators Reward |
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|
Applications/Dilutions
| Dilutions |
|
| Application Notes |
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.
|
Reactivity Notes
Human. Other species not tested.
Packaging, Storage & Formulations
| Storage |
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
|
| Buffer |
PBS (pH 7.4)
|
| Preservative |
No Preservative
|
| Purity |
IgG purified
|
Notes
This product is produced by and distributed for Abnova, a company based in Taiwan.
Alternate Names for CTDSP2 Antibody (4F4)
- carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2
- conserved gene amplified in osteosarcoma
- CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) smallphosphatase 2
- NIF2
- Nuclear LIM interactor-interacting factor 2
- OS4NLI-interacting factor 2
- Protein OS-4
- PSR2
- SCP2EC 3.1.3.16
- Small CTD phosphatase 2
- Small C-terminal domain phosphatase 2
Background
CTDSP2 is one of several small CTD phosphatases (SCP). It has been proposed that SCP activity is an evolutionarily conserved transcriptional regulator that acts globally to silence neuronal genes. In addition, expression of phosphatase CTDSP2 mRNA is enhanced in several cancer cell lines with amplification of the CTDSP2 and CDK4 genes, and CTDSP2 coamplifies with CDK4 in some primary sarcomas. CTDSP2 may contribute to the development of a subset of sarcomas.
