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Transient cerebral ischemia was induced by surgical occlusion of the center cerebral artery. The processes of center cerebral artery occlusion (MCAO) were executed as beforehand

Mice have been sacrificed instantly soon after scoring. Brains had been lower int924416-43-3o six...
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The hypothesis that selective ETA antagonism would boost diuresis by preserving ETB purpose was not supported by the experimental results

The current outcomes recommend that endothelin decreases renal medullary perfusion in normotensive endotoxemic pigs...
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