Product Name :
Lapatinib
Description:
Lapatinib is a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types. Check for active clinical trials or closed clinical trials using this agent.
CAS:
231277-92-2
Molecular Weight:
581.06
Formula:
C29H26ClFN4O4S
Chemical Name:
N-3-chloro-4-[(3-fluorophenyl)methoxy]phenyl-6-(5-[(2-methanesulfonylethyl)amino]methylfuran-2-yl)quinazolin-4-amine
Smiles :
CS(=O)(=O)CCNCC1=CC=C(O1)C1=CC2=C(NC3=CC(Cl)=C(C=C3)OCC3C=C(F)C=CC=3)N=CN=C2C=C1
InChiKey:
BCFGMOOMADDAQU-UHFFFAOYSA-N
InChi :
InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Cilostazol medchemexpress
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.Dantrolene Autophagy
Additional information:
Lapatinib is a synthetic, orally-active quinazoline with potential antineoplastic activity.PMID:32633145 Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types. Check for active clinical trials or closed clinical trials using this agent.|Product information|CAS Number: 231277-92-2|Molecular Weight: 581.06|Formula: C29H26ClFN4O4S|Chemical Name: N-3-chloro-4-[(3-fluorophenyl)methoxy]phenyl-6-(5-[(2-methanesulfonylethyl)amino]methylfuran-2-yl)quinazolin-4-amine|Smiles: CS(=O)(=O)CCNCC1=CC=C(O1)C1=CC2=C(NC3=CC(Cl)=C(C=C3)OCC3C=C(F)C=CC=3)N=CN=C2C=C1|InChiKey: BCFGMOOMADDAQU-UHFFFAOYSA-N|InChi: InChI=1S/C29H26ClFN4O4S/c1-40(36,37)12-11-32-16-23-7-10-27(39-23)20-5-8-26-24(14-20)29(34-18-33-26)35-22-6-9-28(25(30)15-22)38-17-19-3-2-4-21(31)13-19/h2-10,13-15,18,32H,11-12,16-17H2,1H3,(H,33,34,35)|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
